Polyoxyethylene glycol ethers of fatty alcohols used in cloud point extraction of Viola tricolor: Polyphenols solubilization, antioxidant activity studies and molecular dynamic simulations
Authors:
- Paweł Śliwa,
- Karolina Śliwa
Abstract
The following paper proposes a modern method of obtaining an extract from Viola tricolor L. with a high rutin content and enhanced antioxidant activity. Conventional isolation of active substances from plant raw material is high-cost, elaborate and often harmful to the environment. The ultrasonic assistance micelle-mediated extraction method (UAMME) and the cloud-point extraction/separation technique are interesting alternatives. This work discusses the relationship between salt concentration and the cloud-point extraction (CPE) yield. The molecular dynamic simulations investigated the impact of hydrocarbon chain length and the ratio of oxyethylene/oxypropylene units of model surfactants on the interactions between extraction system components. Micellar extract from the Viola tricolor was obtained using C9-11 Pareth-5 at 1 wt/vol% and subsequently concentrated by CPE with the addition of NaCl in concentrations from 5% to 30%. For comparison, water and ethanol extracts were also prepared. Antioxidant properties, polyphenols and flavonoid contents were measured for all samples. The HPLC method was used to determine the rutin concentration. The simulation part of the study confirmed the dependence of bioflavonoid solubilization efficiency on the surfactant structure. The determined descriptors allowed for finding the optimal structure of the model surfactants and gave a hint for their application to obtain extracts with high concentrations of antioxidants.
- Record ID
- CUT9581466a306748dbb9e24d71da92ce5a
- In press
- Yes
- Publication categories
- ;
- Author
- Journal series
- Journal of Surfactants and Detergents, ISSN 1097-3958, e-ISSN 1558-9293
- Issue year
- 2023
- Pages
- [1-7]
- Other elements of collation
- tab.; wykr.; Bibliografia (na s.) - 7; Oznaczenie streszczenia - Abstr.; Numeracja w czasopiśmie - Article in press
- Keywords in English
- cloud point concentration, flavonoids, molecular dynamic simulation, polyethylene/polypropylene glycol ethers of fatty alcohols, ultrasonic assisted micelle-mediated extraction, Viola tricolor
- ASJC Classification
- ; ;
- DOI
- DOI:10.1002/jsde.12697 Opening in a new tab
- URL
- https://aocs.onlinelibrary.wiley.com/doi/full/10.1002/jsde.12697 Opening in a new tab
- Language
- eng (en) English
- Score (nominal)
- 70
- Score source
- journalList
- Score
- Publication indicators
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUT9581466a306748dbb9e24d71da92ce5a/
- URN
urn:pkr-prod:CUT9581466a306748dbb9e24d71da92ce5a
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.