Polymeric and composite carriers of protein and non-protein biomolecules for application in bone tissue engineering
Authors:
- Dagmara Słota,
- Karina Piętak,
- Josef Jampilek,
- Agnieszka Sobczak-Kupiec
Abstract
Conventional intake of drugs and active substances is most often based on oral intake of an appropriate dose to achieve the desired effect in the affected area or source of pain. In this case, controlling their distribution in the body is difficult, as the substance also reaches other tissues. This phenomenon results in the occurrence of side effects and the need to increase the concentration of the therapeutic substance to ensure it has the desired effect. The scientific field of tissue engineering proposes a solution to this problem, which creates the possibility of designing intelligent systems for delivering active substances precisely to the site of disease conversion. The following review discusses significant current research strategies as well as examples of polymeric and composite carriers for protein and non-protein biomolecules designed for bone tissue regeneration.
- Record ID
- CUT35975678f2ef4a4bb517fbd470e6f436
- Publication categories
- ;
- Author
- Journal series
- Materials, ISSN , e-ISSN 1996-1944, Biweekly
- Issue year
- 2023
- Vol
- 16
- No
- 6
- Pages
- [1-37]
- Article number
- 2235
- Other elements of collation
- rys.; tab.; Bibliografia (na s.) - 26-37; Bibliografia (liczba pozycji) - 268; Oznaczenie streszczenia - Abstr.; Numeracja w czasopiśmie - Vol. 16, Iss. 6
- Substantive notes
- This article belongs to the Special Issue: Advanced Functional Materials for Biomedicinal Applications
- Keywords in English
- biomolecules, hormones, flavonoids, lipids, growth factors, protein amino acids, osteopontin, bone sialoprotein, osteocalcin, osteonectin
- ASJC Classification
- DOI
- DOI:10.3390/ma16062235 Opening in a new tab
- URL
- https://www.mdpi.com/1996-1944/16/6/2235 Opening in a new tab
- Related project
- Wielofunkcyjne kompozyty aktywne biologicznie do zastosowań w medycynie regeneracyjnej układu kostnego. . Project leader at PK: , ,
- Language
- eng (en) English
- License
- Score (nominal)
- 140
- Score source
- journalList
- Score
- Publication indicators
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUT35975678f2ef4a4bb517fbd470e6f436/
- URN
urn:pkr-prod:CUT35975678f2ef4a4bb517fbd470e6f436
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.