Preparation and characteristics of alginate microparticles for food, pharmaceutical and cosmetic applications
Authors:
- Anna Łętocha,
- Małgorzata Miastkowska,
- Elżbieta Sikora
Abstract
Alginates are the most widely used natural polymers in the pharmaceutical, food and cosmetic industries. Usually, they are applied as a thickening, gel-forming and stabilizing agent. Moreover, the alginate-based formulations such as matrices, membranes, nanospheres or microcapsules are often used as delivery systems. Alginate microparticles (AMP) are biocompatible, biodegradable and nontoxic carriers, applied to encapsulate hydrophilic active substances, including probiotics. Here, we report the methods most frequently used for AMP production and encapsulation of different actives. The technological parameters important in the process of AMP preparation, such as alginate concentration, the type and concentration of other reagents (cross-linking agents, oils, emulsifiers and pH regulators), agitation speed or cross-linking time, are reviewed. Furthermore, the advantages and disadvantages of alginate microparticles as delivery systems are discussed, and an overview of the active ingredients enclosed in the alginate carriers are presented.
- Record ID
- CUTe69f05faab77405a8c50e63641f78440
- Publication categories
- ;
- Author
- Journal series
- Polymers, ISSN , e-ISSN 2073-4360, Biweekly
- Issue year
- 2022
- Vol
- 14
- No
- 18
- Pages
- [1-32]
- Article number
- 3834
- Other elements of collation
- rys.; schem.; tab.; Bibliografia (na s.) - 23-32; Bibliografia (liczba pozycji) - 247; Oznaczenie streszczenia - Abstr.; Numeracja w czasopiśmie - Vol. 14, Iss. 18, Spec. Iss.
- Substantive notes
- Special Issue: Research Progress in Polymer Hydrogels
- Keywords in English
- alginate, microparticles, active substances, probiotics, encapsulation techniques
- ASJC Classification
- ;
- DOI
- DOI:10.3390/polym14183834 Opening in a new tab
- URL
- https://www.mdpi.com/2073-4360/14/18/3834 Opening in a new tab
- Language
- eng (en) English
- License
- Score (nominal)
- 100
- Score source
- journalList
- Score
- Publication indicators
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUTe69f05faab77405a8c50e63641f78440/
- URN
urn:pkr-prod:CUTe69f05faab77405a8c50e63641f78440
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.