Polymer-ceramic biocomposites based on PVP/histidine/hydroxyapatite for hard tissue engineering applications
Authors:
- Agnieszka Sobczak-Kupiec,
- Agnieszka Maria Tomala,
- Cristina Domínguez López,
- Anna Drabczyk,
- Bożena Tyliszczak
Abstract
Polymer and hydroxyapatite (HAP) composites have growing interest in bone regeneration. Commonly used for these applications is polyvinylpyrrolidone (PVP), which represents excellent biological inertness, is biocompatible, and do not adversely interact with HAP. For this reason, in our studies, we have focused on 3-igreedient biocomposites based on PVP/histidine/HAP investigating their mechanical performance, morphology, swelling property and incubation response. The objective is to determine the effect of histidine on the UV cross-linked hydroxyapatite-polymers composites particularly focused on the role of their composition on structure, mechanical properties, and biocompatibility. The results confirm bioactivity of this material and it desirable features for orthopedics.
- Record ID
- CUT0c1c872b74234d99824a6c2188f9c912
- Publication categories
- ;
- Author
- Journal series
- International Journal of Polymeric Materials, ISSN 0091-4037, e-ISSN 1563-535X
- Issue year
- 2022
- Vol
- 71
- No
- 18
- Pages
- 1380-1392
- Other elements of collation
- fot.; tab.; wykr.; Bibliografia (na s.) - 1391-1392; Bibliografia (liczba pozycji) - 31; Oznaczenie streszczenia - Abstr.; Data udostępnienia on-line - 2021-08-17; Numeracja w czasopiśmie - Vol. 71, Iss. 18
- Keywords in English
- hydroxyapatite, drug delivery, hydrogels, bio mechanical properties, swelling properties, incubation
- ASJC Classification
- ; ;
- DOI
- DOI:10.1080/00914037.2021.1963725 Opening in a new tab
- URL
- https://www.tandfonline.com/doi/full/10.1080/00914037.2021.1963725 Opening in a new tab
- Related project
- Wielofunkcyjne kompozyty aktywne biologicznie do zastosowań w medycynie regeneracyjnej układu kostnego. . Project leader at PK: , ,
- Language
- eng (en) English
- Score (nominal)
- 70
- Score source
- journalList
- Score
- Publication indicators
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUT0c1c872b74234d99824a6c2188f9c912/
- URN
urn:pkr-prod:CUT0c1c872b74234d99824a6c2188f9c912
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.