Metal and bimetallic nanoparticles: flow synthesis, bioactivity and toxicity
Authors:
- Olga Długosz,
- Marta Sochocka,
- Michał Ochnik,
- Marcin Banach
Abstract
Hypothesis: Metal nanoparticles are used as additives in commercial products due to their antimicrobial properties. Apart from their high biocidal activity, it is widely observed that silver nanoparticles are toxic. Simultaneously, copper nanoparticles show fungicidal properties, but with limited effectiveness. Hence, it is suggested that a combination of Ag nanoparticles with Cu nanoparticles may decrease the toxic effects of silver while maintaining their high bioactivity. Experiments: This paper presents the properties of Ag and Cu metal nanoparticles, and Ag-Cu and Cu-Ag bimetallic nanoparticles, synthesised in a continuous microwave reactor. The size of the metal nanoparticles obtained was in the range of 27–97 nm, and the size of the bimetallic nanoparticles was in the range of 32–184 nm, depending on the microwave irradiation, residence time, pH of the solution and concentrations of the reagents. Findings: Silver nanoparticles of particle size 97 nm revealed the highest antimicrobial activity (MIC = 10 mg/dm3 ). Simultaneously, silver nanoparticles did not show viral properties, compared to the copper and bimetallic nanoparticles, for which the virus titre was 1.06–1.50 log TCID50/cm3 . In contrast to pure metal nanoparticles, the combination of silver and copper in bimetallic systems generated nanoparticles with no genotoxicity (rac(-)/rac(+) < 1.2).
- Record ID
- CUT27bc4665d0614c908e8f7ab2c8d48ac2
- Publication categories
- ;
- Author
- Journal series
- Journal of Colloid and Interface Science, ISSN 0021-9797, e-ISSN 1095-7103
- Issue year
- 2021
- Vol
- 586
- Pages
- 807-818
- Other elements of collation
- fot.; rys.; tab.; wykr.; Bibliografia (na s.) - 818; Bibliografia (liczba pozycji) - 43; Oznaczenie streszczenia - Abstr.; Data udostępnienia on-line - 2020-11-05; Numeracja w czasopiśmie - Vol. 586
- Keywords in English
- metal nanoparticles, bimetallic nanoparticles, antiviral, bioactivity, genotoxicity, phytotoxicity
- DOI
- DOI:10.1016/j.jcis.2020.11.005 Opening in a new tab
- URL
- https://www.sciencedirect.com/science/article/pii/S0021979720315034 Opening in a new tab
- Language
- eng (en) English
- Score (nominal)
- 100
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUT27bc4665d0614c908e8f7ab2c8d48ac2/
- URN
urn:pkr-prod:CUT27bc4665d0614c908e8f7ab2c8d48ac2
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.