The effect of antibacterial particle incorporation on the mechanical properties, biodegradability, and biocompatibility of PLA and PHBV composites
Authors:
- Karolina Mazur,
- Raminder Singh,
- Ralf P. Friedrich,
- Hatice Genç,
- Harald Unterweger,
- Kamila Sałasińska,
- Rafał Bogucki,
- Stanisław Kuciel,
- Iwona Cicha
Abstract
The composites based on polylactide (PLA) and poly (3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) (PHBV) with the addition of antibacterial particles: silver (Ag) and copper oxide (CuO) are characterized. Basic mechanical properties and biodegradation processes, as well as biocompatibility of materials with human cells are determined. The addition of Ag or CuO to the polymers do not significantly affect their mechanical properties, flammability, or biodegradation rate. However, several differences between the base materials are observed. PLA‐based composites have higher tensile and impact strength values, while PHBV‐based ones have a higher modulus of elasticity, as well as better mechanical properties at elevated temperatures. Concerning biocompatibility, each of the tested materials support the growth of fibroblasts over time, although large differences are observed in the initial cell attachment. The analysis of hydrolytic degradation effects on the structure of materials shows that PHBV degrades much faster than PLA. The results of this study confirm the good potential of the investigated biodegradable polymer composites with antibacterial particles for future biomedical applications.
- Record ID
- CUTd677633a7fb242a7a415eed6ea76e2d1
- Publication categories
- ;
- Author
- Journal series
- Macromolecular Materials and Engineering, ISSN 1438-7492, e-ISSN 1439-2054, [0003-3146]
- Issue year
- 2020
- Vol
- 305
- No
- 9
- Pages
- [1-15]
- Article number
- 2000244
- Other elements of collation
- il. (w tym kolor.); Bibliografia (na s.) - 15; Bibliografia (liczba pozycji) - 48; Oznaczenie streszczenia - Abstr.; Numeracja w czasopiśmie - Vol. 305, Iss. 9
- Keywords in English
- biocompatibility, biocomposites, copper oxide particles, poly (3-hydroxybutyrate-co-3-hydroxyvalerate), polylactide, silver particles
- DOI
- DOI:10.1002/mame.202000244 Opening in a new tab
- URL
- https://onlinelibrary.wiley.com/doi/full/10.1002/mame.202000244 Opening in a new tab
- Language
- eng (en) English
- License
- Score (nominal)
- 70
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUTd677633a7fb242a7a415eed6ea76e2d1/
- URN
urn:pkr-prod:CUTd677633a7fb242a7a415eed6ea76e2d1
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.