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Cyclodextrin-modified poly(octamethylene citrate) polymers towards enhanced sorption properties
Authors:
- Wiktor Kasprzyk,
- Szczepan Bednarz,
- Dariusz Bogdał,
- Guillermo A. Ameer,
- Tomasz Świergosz
Abstract
Herein, we describe the synthesis of poly(1,8-octamethylene citrate) materials modified in the bulk with 2-hydroxypropyl-β-cyclodextrin (cPOCCD), biodegradable elastomers with intrinsic sorption properties for drug delivery. The chemical structure, physicochemical properties, in vitro drug loading and release profiles of cPOCCD were investigated. Thus, cPOCCD polyesters absorb the studied drugs more effective and release them for a longer period of time than poly(1,8-octamethylene citrate) materials not containing cyclodextrins.
- Record ID
- CUT2cbed26fa5df4fac81bf34231f66036e
- Publication categories
- ;
- Author
- Journal series
- Soft Matter, ISSN 1744-683X, e-ISSN 1744-6848
- Issue year
- 2020
- Vol
- 16
- No
- 13
- Pages
- 3311-3318
- Other elements of collation
- rys.; tab.; wykr.; Bibliografia (na s.) - 3317-3318; Bibliografia (liczba pozycji) - 48; Oznaczenie streszczenia - Streszcz. ang.; Numeracja w czasopiśmie - Vol. 16, Iss. 13
- Keywords in English
- cyclodextrin, modifications, poly(octamethylene citrate), polymers, sorption, properties
- DOI
- DOI:10.1039/C9SM02075F Opening in a new tab
- URL
- https://pubs.rsc.org/en/content/articlelanding/2020/sm/c9sm02075f#!divAbstract Opening in a new tab
- Related project
- Nowe fluorescencyjne poliestry o właściwościach przeciwutleniających do zastosowań w inżynierii naczyń krwionośnych. . Project leader at PK: , ,
Projects financed by NSC [Projekty finansowane przez NCN] - Language
- eng (en) English
- Score (nominal)
- 100
- Publication indicators
- = 9
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUT2cbed26fa5df4fac81bf34231f66036e/
- URN
urn:pkr-prod:CUT2cbed26fa5df4fac81bf34231f66036e
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.