Anti-hypochlorite and catalytic activity of commercially available moringa oleifera diet supplement
Authors:
- Karolina Starzak,
- Bernadette Creaven,
- Arkadiusz Matwijczuk,
- Alicja Matwijczuk,
- Dariusz Karcz
Abstract
Aiming at the assessment of the pro-health, and especially anti-hypochlorite properties of Moringa oleifera species a representative, commercially available Moringa oleifera dietary supplement was used as a substrate for the preparation of aqueous Moringa extract. The anti-hypochlorite activity of the extract was assessed using the hypochlorite-specific coumarin-based fluorescence turn-off sensor, namely 7-diethylamino-coumarin-3-carboxylic acid (7-DCCA). This compound was synthesized via the Knoevenagel condensation of 4-diethylamino-2-hydroxybenzaldehyde with Meldrum’s acid and the Moringa extract was employed as a medium and catalyst. Moreover, the total phenolic content (TPC) as well as the reactive oxygen species (ROS)–scavenging ability of the aqueous Moringa extract were determined. The results obtained demonstrated the applicability of Moringa extract as an anti-hypochlorite agent. Additionally, the satisfactory yield of the 7-DCCA obtained suggests the usefulness of the extract as a catalyst and the reaction medium. The antioxidative potential of the extract was notably lower than that of the standard (TROLOX). Determination of TPC in 100 g of the dry weight (DW) of studied material revealed a high number of polyphones present.
- Record ID
- CUT70871b4bbaae497fb6fffa6c46a313bc
- Publication categories
- ;
- Author
- Journal series
- Molecules, ISSN , e-ISSN 1420-3049, Biweekly
- Issue year
- 2019
- Vol
- 24
- No
- 18
- Pages
- [1-12]
- Article number
- 3330
- Other elements of collation
- schem.; tab.; wykr.; Bibliografia (na s.) - 11-12; Bibliografia (liczba pozycji) - 36; Oznaczenie streszczenia - Abstr.; Numeracja w czasopiśmie - Vol. 24, Iss. 18, Spec. Iss.
- Substantive notes
- Special Issue: Natural Polyphenols and Health
- Keywords in English
- moringa oleifera, hypochlorite, scavenging, free radicals, antioxidative potential, inflammation, coumarins, DPPH
- DOI
- DOI:10.3390/molecules24183330 Opening in a new tab
- URL
- https://www.mdpi.com/1420-3049/24/18/3330 Opening in a new tab
- Language
- eng (en) English
- License
- Score (nominal)
- 140
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUT70871b4bbaae497fb6fffa6c46a313bc/
- URN
urn:pkr-prod:CUT70871b4bbaae497fb6fffa6c46a313bc
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.