Hydroxyapatite/silver nanoparticles powders as antimicrobial agent for bone replacements
Authors:
- Agnieszka Sobczak-Kupiec,
- Dagmara Malina,
- Regina Kijkowska,
- Wioletta Florkiewicz,
- Klaudia Pluta,
- Zbigniew Wzorek
Abstract
This paper reports a superficial morphological modification of the hydroxyapatite grains obtained by in situdeposition of Ag nanoparticles on natural origin calcium phosphate powder. Ceramic material was prepared in three stage bone treatment, including hydrolysis with a lactic acid, pre-calcination, and proper calcination. Subsequently, the Ag nanoparticles were synthesized by chemical reduction of Ag+by sodium borohydride in a solution of polyvinylpyrrolidone and in presence of hydroxyapatite. Such-prepared materials were investigated with X-ray diffraction, Fourier-transformed infrared spectroscopy, atomic absorption spectrometry and scanning electron microscopy with energy dispersive spectroscopy. Furthermore, Ca/P molar ratio was calculated and microbiological tests were performed to investigate materials antimicrobial activity. The appearance of Ag nanoparticles located on phosphate surface was confirmed by SEM analysis, and no chemical bonding with hydroxyapatite was recorded by IR and XRD techniques. Additionally, the biological assessment revealed bactericidal effect on Escherichia coli and Staphylococcus aureus, while slightly affected on Enterococcus faecalis viability.
- Record ID
- CUTde7960c2f16b419490fb01847aa4d7fa
- Publication categories
- ;
- Author
- Journal series
- Croatica Chemica Acta, ISSN 0011-1643, e-ISSN 1334-417X
- Issue year
- 2019
- Vol
- 92
- No
- 1
- Pages
- [1-10]
- Other elements of collation
- fot.; tab.; wykr.; Bibliografia (na s.) - 9-10; Bibliografia (liczba pozycji) - 58; Oznaczenie streszczenia - Abstr.; Numeracja w czasopiśmie - Vol. 92, No. 1
- Keywords in English
- hydroxyapatite, silver nanoparticles, antibacterial activity, surface modification
- DOI
- DOI:10.5562/cca3463 Opening in a new tab
- URL
- https://hrcak.srce.hr/217460 Opening in a new tab
- Related project
- Opracowanie składu powłok kompozytowych modyfikowanych nanocząstkami metalicznymi zawierających fosforany wapnia pochodzenia naturalnego i syntetycznego. . Project leader at PK: , ,
Projects financed by NSC [Projekty finansowane przez NCN] - Language
- eng (en) English
- License
- Score (nominal)
- 20
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUTde7960c2f16b419490fb01847aa4d7fa/
- URN
urn:pkr-prod:CUTde7960c2f16b419490fb01847aa4d7fa
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.