Preparation and cytotoxicity of chitosan-based hydrogels modified with silver nanoparticles
Authors:
- Bożena Tyliszczak,
- Anna Drabczyk,
- Sonia Kudłacik-Kramarczyk,
- Katarzyna Bialik-Wąs,
- Regina Kijkowska,
- Agnieszka Sobczak-Kupiec
Abstract
Chitosan based hydrogels are commonly applied in various fields of medicine and pharmacy. Modification of hydrogel polymers using nanosilver particles may result in formation of materials with enhanced antibacterial properties. In this article synthesis of hydrogel materials based on chitosan and modified with silver nanoparticles is presented. First, preparation and characterization of silver nanoparticles using UV–vis spectroscopy has been shown. Hydrogels modified with nanosilver particles were subjected to the measurements of swelling ability and in vitro tests in distilled water and Simulated Body Fluid (SBF), respectively. Additionally, evaluation of antibacterial properties against Staphylococcus aureus and Enterococcus faecalis as well as results of cytotoxicity of hydrogel materials modified with silver nanoparticles conducted by means of XTT and MTT assays using dermis cells BJ (CRL-2522TM) have been presented.
- Record ID
- CUTd9e4ed68fa7643f8b9551da97a4c0c89
- Publication categories
- ;
- Author
- Journal series
- Colloids and Surfaces B-Biointerfaces, ISSN 0927-7765, e-ISSN 1873-4367
- Issue year
- 2017
- Vol
- 160
- Pages
- 325-330
- Other elements of collation
- rys.; tab.; wykr.; Bibliografia (na s.) - 329-330; Bibliografia (liczba pozycji) - 30; Oznaczenie streszczenia - Abstr.; Numeracja w czasopiśmie - Vol. 160
- Substantive notes
- ES, 22.12.2017 - Regina Kijkowska - prac emerytowany
- Keywords in English
- chitosan, hydrogels, antibacterial properties, cytotoxicity, nanosilver
- DOI
- DOI:10.1016/j.colsurfb.2017.09.044 Opening in a new tab
- URL
- http://www.sciencedirect.com/science/article/pii/S0927776517306227 Opening in a new tab
- Related project
- Zastosowanie Beetosanu do otrzymywania nowoczesnych biomedycznych matryc hydrożelowych. . Project leader at PK: , ,
Projects financed by NCRD [Projekty finansowane przez NCBiR (NCBR (] - Language
- eng (en) English
- Score (nominal)
- 35
- Publication indicators
- = 54
- Additional fields
- Indeksowana w: Web of Science, Scopus
- Uniform Resource Identifier
- https://cris.pk.edu.pl/info/article/CUTd9e4ed68fa7643f8b9551da97a4c0c89/
- URN
urn:pkr-prod:CUTd9e4ed68fa7643f8b9551da97a4c0c89
* presented citation count is obtained through Internet information analysis, and it is close to the number calculated by the Publish or PerishOpening in a new tab system.